Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer.
Mohammadreza Alizadeh-Ghodsi,
Katie L Owen,
Scott L Townley,
Damien Zanker,
Samuel PG Rollin,
Adrienne R Hanson,
Raj Shrestha,
John Toubia,
Tessa Gargett,
Igor Chernukhin,
Jennii Luu,
Karla J Cowley,
Ashlee Clark,
Jason S Carroll,
Kaylene J Simpson,
Jean M Winter,
Mitchell G Lawrence,
Lisa M Butler,
Gail P Risbridger,
Benjamin Thierry,
Renea A Taylor,
Theresa E Hickey,
Belinda S Parker,
Wayne D Tilley,
Luke A Selth
Apr 15, 2023
UNLABELLED: Inhibiting the androgen receptor (AR), a ligand-activated transcription factor, with androgen deprivation therapy is a standard-of-care treatment for metastatic prostate cancer. Paradoxically, activation of AR can...